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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
21.21
Human Site:
S1081
Identified Species:
35.9
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1081
L
L
N
E
D
P
K
S
L
D
I
F
I
K
A
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1081
L
L
N
E
D
P
K
S
L
D
I
F
I
K
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
S1081
L
L
H
K
D
P
K
S
L
D
I
F
I
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
S1081
L
L
Q
K
D
P
K
S
L
D
L
F
I
K
A
Rat
Rattus norvegicus
NP_001101888
2143
241191
S1081
L
L
Q
K
D
S
K
S
L
D
L
F
I
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S1091
L
L
C
K
N
Q
Q
S
L
D
L
F
I
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
C1077
L
L
V
K
D
P
R
C
L
E
V
F
I
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
L1053
R
K
D
L
A
W
K
L
F
E
D
S
F
A
Q
Honey Bee
Apis mellifera
XP_393800
2028
231830
V1008
K
A
L
T
V
E
Q
V
W
Q
L
F
E
A
N
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
A683
Q
Q
H
L
A
V
N
A
I
R
K
I
L
E
H
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
K668
K
I
L
D
L
L
G
K
N
M
A
A
M
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
M1009
K
D
L
G
I
M
L
M
R
D
E
I
V
K
L
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
F802
L
P
L
D
S
D
I
F
V
S
I
L
N
Q
N
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
A821
K
I
W
S
S
M
K
A
E
T
Q
F
S
T
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
80
N.A.
80
73.3
N.A.
N.A.
53.3
N.A.
53.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
N.A.
86.6
N.A.
86.6
N.A.
20
20
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
15
0
0
15
0
0
8
8
0
15
50
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
15
43
8
0
0
0
50
8
0
0
0
0
% D
% Glu:
0
0
0
15
0
8
0
0
8
15
8
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
65
8
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
15
0
0
8
0
8
0
8
0
29
15
50
0
0
% I
% Lys:
29
8
0
36
0
0
50
8
0
0
8
0
0
50
0
% K
% Leu:
58
50
29
15
8
8
8
8
50
0
29
8
8
0
8
% L
% Met:
0
0
0
0
0
15
0
8
0
8
0
0
8
0
0
% M
% Asn:
0
0
15
0
8
0
8
0
8
0
0
0
8
0
15
% N
% Pro:
0
8
0
0
0
36
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
15
0
0
8
15
0
0
8
8
0
0
15
15
% Q
% Arg:
8
0
0
0
0
0
8
0
8
8
0
0
0
8
0
% R
% Ser:
0
0
0
8
15
8
0
43
0
8
0
8
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
8
0
8
8
0
8
8
0
8
0
8
0
0
% V
% Trp:
0
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _